Professor
Office Location: UH 205
Phone Number: (262) 472-5137
Email Address: wollerm@uww.edu

Michael J. Woller. 1995. Animal Physiologist, Endocrinologist

Ph.D., 1991, Endocrinology and Reproductive Physiology, University of Wisconsin-Madison

Associate Professor teaching Biological Foundations, Biology of the Brain, Introduction to Cell Biology, Animal Physiology, and Endocrinology

Biological Sciences Master Advisor and Pre-Dentistry Advisor

Research interests center on measurement of complex neuroendocrine signals from the hypothalamus, observation of how pituitary cells process these complex signals, and measurement of endocrine release from the pituitary gland. Most of this work involves the central mechanisms for reproductive function. This laboratory uses whole animal models (rats, rhesus monkey, common marmoset) with several sophisticated surgical procedures to isolate various components of the tissues which interact to regulate the hormone production and release involved in neural reproductive function. Other methods employed include immunocytochemistry, cell culture, radioimmunoassay, and perifusion of cultured tissues.

Woller, M.J., Tessmer, S., Neff, D., Ada Nguema, A., Van Roo, B., Waechter-Brulla, D. Leptin stimulates gonadotropin releasing hormone release from cultured intact hemihypothalami and enzymatically dispersed neurons. Experimental Biology and Medicine 226:591-596, 2001.

Al-Kindi, A.Y., Mahmoud, I.Y., Woller, M.J. Ultrastructural changes in granulosa cells and plasma steroid levels after administration of luteinizing hormone-releasing hormone in the western painted turtle, Chrysemys picta. Tissue and Cell 33:1-7, 2001.

Vella, S., Gussick, J., Woller, M.J., Waechter-Brulla, D. Cell perifusion for extended study of hormone release in the rat pituitary. Methods in Cell Science, In Press, 2002.

Gore, A.C., Oung, T., Woller, M.J. Age-related changes in hypothalamic gonadotropin-releasing hormone (GnRH) and NMDA receptor gene expression, and their regulation by estrogen in the female rat. Journal of Neuroendocrinology, 14:300-309, 2002.

Gore, A.C., Oung, T., Yung, S., Flagg, R.A., Labowitz, D.A., Rosenberg, J.J., Woller, M.J. Neuroendocrine mechanisms for reproductive senescence in the female rat. Endocrine 13:315-323, 2000.

Waecther-Brulla, D., Woller, M.J. The Original Biotechnology: Brewing An Undergraduate Education. Journal of Industrial Microbiology and Biotechnology, 2000.

Woller, M.J., Nichols, E., Herdendorf, T., Tutton, D. Release of Luteinizing Hormone-Releasing Hormone from enzymatically dispersed rat hypothalamic explants is pulsatile. Biology of Reproduction 59: 587-590, 1998.

Woller, M.J., Campbell, G.T., Blake, C.A. Changes in percentages of adenohypophysial gonadotrophs associated with the sex- specific, selective increase in serum follicle-stimulating hormone concentration in the juvenile female hamster. Biology of Reproduction 54: 800-808, 1996.

Woller, M.J., Campbell, G.T., Blake, C.A. Neuropeptide Y and luteinizing hormone releasing hormone synergize to stimulate the development of cellular follicle-stimulating hormone in the female hamster adenohypophysis. Journal of Neuroendocrinology 7:733-736, 1995.